Following the prescribed dosages is vital to ensure that the treatment using Lagundi will render positive results,” the project leader of the Lagundi clinical trials, Dr. Cecilia Maramba-Lazarte, reminds the public.

 

Results of the Lagundi clinical trial conducted by the University of the Philippines - Manila (UPM) with support from the Department of Science and Technology - Philippine Council for Health Research and Development (DOST-PCHRD) show that mild COVID-19 patients may take specific dosages of the Lagundi tablet or syrup three times a day for ten days to improve their symptoms.

 

Adult patients may take the 600mg tablet or 5mL of the 600mg syrup thrice daily. Meanwhile, the dosage requirement for pediatric patients would vary depending on their age range. The 300mg syrup may be taken thrice daily by children, following the suggested dosage per intake: 2.5 to 5mL for ages 2 to 4, 5mL for ages 4 to 6, and 7.5 to 10mL for ages 6 to 12. Teens aged 12 and older may also take the 600 mg tablet thrice a day. Following these guidelines, the use of the medicine may alleviate mild COVID-19 symptoms, especially the loss of sense of smell for patients.

 

While both the Lagundi syrup and tablet are considered to be over-the-counter medicines, patients are still advised to take precautions in using the products and avoid over-dosage. During treatment, the research team also recommends that patients continue to consult with healthcare professionals, isolate, and monitor vital signs.

 

"Our team conducted this study because we want to help our patients in battling COVID-19," Dr. Maramba-Lazarte says. “We hope that everyone who will use the Lagundi syrup and tablet will adhere to these evidence-based guidelines for best results,” she adds.


The Council has always been committed to supporting R&D initiatives that will help alleviate the healthcare burdens of the Filipino, which are not limited to COVID-19,” DOST-PCHRD Executive Director Dr. Jaime C. Montoya says. “Part of this mission is to make sure that every initiative, such as this Lagundi clinical trial, will benefit and serve the needs of the Filipino,” he adds.

 

Formulated under the National Integrated Research Program on Medicinal Plants (NIRPROMP), the FDA-approved Lagundi product has long been used for cough and asthma relief. Lagundi is also included in the homecare kit for mild COVID-19 patients of the Philippine Health Insurance Corporation (PhilHealth).

 

According to the latest case bulletin of the Department of Health (DOH), the majority of the confirmed COVID-19 cases are mild or asymptomatic. Home care and quarantine are currently allowed for mild and asymptomatic cases.

With the goal of reaching a wider audience in the dissemination of health research results in Twitter and Facebook, the Philippine Council for Health Research and Development of the Department of Science and Technology organized the Visualize Health Research 2.0, A Visual Abstract Contest.

Launched during the Kick Off event of the 40th Anniversary celebration of the Council last 17 January 2022, the contest is open to all creative Filipinos residing in the Philippines except to PCHRD employees and their immediate family members, and PCHRD’s project team members. Joining the contest is FREE of charge. 
Three individuals have an opportunity to win a cash prize amounting to P10,000, P6,000, and P3,000.

Here's the contest guidelines:

Eligibility
  • The contest is open to all creative Filipinos residing in the Philippines. 
  • Employees of PCHRD and members of their immediate family, and project team members are not eligible to join the contest.
 
Mechanics
  • The contestant must create a visual abstract on one (1) of the following published research studies of the Council (2019-2021):
  1. Development of a mobile game to influence behavior determinants of HIV service uptake among key populations in the Philippines: User-centered design process.  
  2. Is the Philippines ready for HIV self-testing? 
  3. Development and Evaluation of a Culturally Sensitive Food Frequency Questionnaire for the Assessment of Prebiotic and Probiotic Intake of Urban-living, Low-to-medium-income Women. 
  4. Prevalence and Molecular Characteristics of MRSA Nasal Carriage Among Hospital Care Workers in a Tertiary Hospital in the Philippines.
  5. Effect of heavy metals on ventricular repolarization and depolarization in the Metropolitan Manila Development Authority (MMDA) traffic enforcers’ health study 
  6. MicroRNA92a promotes cell proliferation, migration and survival by directly targeting the tumor suppressor gene NF2 in colorectal and lung cancer cells. 
  7. Non-Redundant and Overlapping Oncogenic Readouts of Non-Canonical and Novel Colorectal Cancer KRAS and NRAS Mutants. 
  8. Identification and validation of mRNA 3'untranslated regions of DNMT3B and TET3 as novel competing endogenous RNAs of the tumor suppressor PTEN. 
  9. Mutation-Associated Phenotypic Heterogeneity in Novel and Canonical PIK3CA Helical and Kinase Domain Mutants 
  10. NRAS mutant E132K identified in young-onset sporadic colorectal cancer and the canonical mutants G12D and Q61K affect distinct oncogenic phenotypes
  11. High rates of tenofovir failure in a CFR01 AE-predominant HIV epidemic in the Philippines
  12. Factors influencing health-seeking behavior among overseas Filipino workers
  13. Patient-cost survey for tuberculosis in the context of patient-pathway modelling. 
  • Submission of visual abstract poster entries will be via email (This email address is being protected from spambots. You need JavaScript enabled to view it.) with the following subject format: Visual Abstract_Last Name) (ex. Visual Abstract_Dela Cruz). Deadline of submission of entries is on 17 February 2022.
  • Winners will be announced during the 40th PCHRD Anniversary Main Event on 17 March 2022.
Visual Abstract Contest Piece
  • A visual abstract is a visual summary of the information contained within a research abstract. Similar to the actual text abstract of a research article, it is meant to communicate the key findings of the article in a shorter format. You may use this as reference in creating a visual abstract. 
  • Visual abstract specifications: 
    • Dimension: 1080px X 1350px
    • Resolution: 300ppi
    • Orientation: Portrait
    • Must contain the title and author/s of the chosen research study and DOST PCHRD logo and official 40th Anniversary logo (logos here). 
    • Maximum file size of 5 MB in JPEG format. 
Criteria for Judging
  • Clarity of message – 35%
  • Correctness and accuracy of translation – 35%
  • Relevant creativity and originality – 20%
  • Visual Impact – 10 %
Reminders
  • Strictly one entry per participant only. 
  • The contest piece submitted shall be created specifically for this Contest and has not been used commercially.
  • The participant warrants and represents that they own all rights to the Entry, their Entry is the original work of the participant, does not contain any third-party designs, does not infringe any third party’s rights, complies with all laws and regulations, and does not contain defamatory statements, or invade privacy, publicity or other rights of any third party. Entries containing prohibited or inappropriate content will be disqualified, as determined by the Council in its sole discretion.
  • After the contest, submitted visual abstract entries will become property of the Council.
  • A special prize will be given to the People’s Choice Award that will be conducted through PCHRD social media accounts. 
For more information, kindly send an email to Grace Ann Cenon (This email address is being protected from spambots. You need JavaScript enabled to view it.).


The Best Mentor Award is awarded biennially to recognize mentors in health research who have built the capacities of researchers in the health sector and, in the process, propelled significant advances in the Philippine National Health Research System’s (PNHRS) thrusts as identified in the National Unified Health Research Agenda (NUHRA).

Awardees are selected per cluster (Luzon, Visayas, Mindanao and NCR) and categorized according to their mentees (Undergraduate Students, Graduate Students and Junior/Early Career Researchers). For this year’s call, the following are the cluster winners per category:

Undergraduate Category

NAME

INSTITUTION

CLUSTER

Rev. Fr. Alfredo V. Corpuz

University ofNorthern Philippines

Luzon

Ms. Carol Joy P. Remaneses

Aklan State University

Visayas


Graduate Category

NAME

INSTITUTION

CLUSTER

Dr. Julius T. Capili

Cagayan State University

Luzon

Dr. Rheajane A. Rosales

Samar State University

Visayas

Dr. Mylene M. Uy

Mindanao State University – Iligan Institute of Technology

Mindanao

Dr. Agnes L. Castillo

University of Santo Tomas

NCR


Junior/Early Career Researchers Category

NAME

INSTITUTION

CLUSTER

Dr. Jonel P. Saludes

University of San Agustin

Visayas

Dr. Erna C. Arollado

UP Manila

NCR

The cluster winners will receive plaques of recognition and cash prizes amounting to either Fifty Thousand Pesos (Undergraduate and Graduate Category) or One Hundred Thousand Pesos (Junior/Early Career Researchers Category), depending on their category. 

The national winners per category will be selected among the cluster winners. The announcement of the national winners and the awarding of winners will be in March 2022 during the 40th PCHRD Anniversary Celebration.

Congratulations to the qualified grantees of the 2021 Undergraduate Thesis Grant in Natural Products!

The Department of Science and Technology-Philippine Council for Health Research and Development (DOST-PCHRD) Undergraduate Thesis Grant in Natural Products provides fund support to undergraduate students who will conduct their thesis on natural products. The program aims to sustain a research culture in natural products to increase the number of research and later on build a pool of researchers/experts specializing in the field. The program supports the Tuklas Lunas (Drug Discovery and Development) program of the DOST-PCHRD, which aims to develop safe, effective, and affordable alternative drugs from the country’s natural resources.

Every year, thesis grants are given to two qualified (2) undergraduate entries per region. For this year’s call, the following are the qualified entries from the regions:

  1. Phytochemical Screening and Pharmacological Evaluation of Rhizophora muscronata Bark Extracts Collected from Lucena City, Philippines, Southern Luzon State University (SLSU)

The study aims to determine the phytochemical constituents and evaluate the pharmacological potentials of Rhizophora mucronata bark extract. Mr. John Joshua Bellen, grantee, will implement the said project under the mentorship of his thesis adviser, Mr. Roberth Riggs L. Rondilla.

  1. Morphological, Molecular and Phytochemical Analyses of the Three Medicinal Plants used as a ritual liniment by the Subanons of Sibuco, Zamboanga del Norte, Western Mindanao State University 

The study aims to conduct morphoanatomical, molecular and phytochemical analyses of the three medicinal plants used as ritual liniment by the Subanons of Sibuco, Zamboanga del Norte. The grantees, Moyanrose B. Edding, Shaina Mae S. Evangelista and Yusof K. Ortiz, will implement the project under the mentorship of  Dr. Genelyn Madjos.

  1. Antitumor and Antiangiogenic Activities of Crude Methanolic Seaweed Extracts of Solieria robusta (Greville) Kylin, 1932, Western Mindanao State University 

The study aims to evaluate the potential of Solieria robusta Crude Methanolic Extracts as an anticancer agent by investigating its antitumor and antiangiogenic activities in the MTT (3-[4, 5-dimethylthiazol-2-yl]-2, 5 diphenyl tetrazolium bromide) Assay and in the duck chorioallantoic membrane (CAM) Assay, respectively. Mr. Wenzell E. Perian, grantee, will implement the said project under the mentorship of his thesis adviser, Dr. Melbert C. Sepe.

  1. Exploring the Philippine Endemic Hornstedtia conoidea Fruit and Etlingera elatior Inflorescence: Its Metabolite Profile and Antioxidant Activity and its Potential for Functional Powder Development, Central Mindanao University

The study aims at profiling the metabolites in the plants to characterize the components, as well as to provide baseline information in order to assess the safety of the endemic fruit that is consumed by the locals without safety verification. Mr. Jason C. Alcano, grantee, will implement the said project under the mentorship of his thesis adviser, Dr. Gina B. Barbosa.

  1. Phytochemical Analysis and In vitro Antiurolithiatic Activity Evaluation of Tangisang-bayauak (Ficus variegata Blume) Leaf Extract, University of Southern Mindanao

The study aims to determine the presence of the phytochemicals and evaluate the in vitro antiurolithiatic activity of tangisang-bayauak (Ficus variegata Blume) leaf extract. 

Ms. Ivy Jane M. Natavio, grantee, will implement the project under the mentorship of her thesis adviser,  Mr. Randy B. Tumacder.

  1. Phytochemical Analysis and Evaluation of the In vitro Antiurolithiatic Activity of Alim (Melanolepis multiglandulosa (Reinw. ex Blume) Reichb. & Zoll.) Fruit and Leaf Extracts against Calcium Oxalate Kidney Stone, University of Southern Mindanao

The study aims to  determine the presence of phytochemicals and evaluate the antiurolithiatic activity of M. multiglandulosa fruit and leaf extracts against calcium oxalate kidney stones. Mr. Mc Lin G. Data, grantee, will implement the project under the mentorship of his thesis adviser,  Mr. Randy B. Tumacder.

  1. Anti-angiogenicity and Teratogenicity of Melanolepis multiglandulosa (Reinw. Ex. Blume) Stem Bark and Leaf Crude Ethanolic Extracts in Mallard Ducks (Anas Plathyrynchos) Embryo, Mindanao State University- Main Campus

The study aims to evaluate the anti-angiogenic and teratogenic effects of the stem bark and leaf crude ethanolic extract of M. multiglandulusa in A. platyrhynchos embryo. Ms. Amerah D. Samporna, grantee, will implement the project under the mentorship of Dr. Beverly B. Amparado.

After completion of their projects in May 2022, a competition will be held for selected qualified students to recognize their innovative work on natural products.

The Philippine National Health Research System (PNHRS) announced the selected outstanding health research programs in 2021 during the 14th PNHRS Week Celebration last August 13, 2021.

The Alberto G. Romualdez, Jr. Outstanding Health Research Award (AROHRA) gives recognition to a research program or project that has demonstrated the link between research and practice through the utilization of research findings in the health delivery system. The award, given every three years, has two (2) categories, namely: Biomedical Research and Health Services Research. The winners of AROHRA will receive a trophy and a cash prize amounting to Five Hundred Thousand Pesos (PHP 500,000.00).

This year, the Molecular Diagnostics and Cellular Therapeutics Laboratory of the Lung Center of the Philippines won under the biomedical research category for their program entitled “Autologous Dendritic Cell Vaccine as Innovative Therapy for Cancer.” The said program, headed by Dr. Ma. Teresa Barzaga, offers a promising complementary therapy for cancer.

                    

The program also gives patients an option for an innovative and safe therapy in a form of active immunotherapy using dendritic cells which is derived from patients’ own blood stem to trigger the immune response against the disease and poses minimal to zero adverse effects.

On the other hand, the Food and Nutrition Research Institute of the Department of Science and Technology (DOST-FNRI) won under the health services research category for their program entitled, “Malnutrition Reduction Program (MRP): Moving towards Sustained Implementation.” The MRP program, headed by Dr. Mario V. Capanzana, contributes to address the malnutrition problem among young children across the country especially in rural areas.



The two components of the program are technology transfer of complementary food or bringing the technology to the regions to address the supply side of the program which also generates livelihood for the local government units (LGUs) and state universities and colleges (SUCs) and the DOST PINOY (Package for the Improvement of Nutrition of Young Children) intervention strategy or the combining of feeding of rice-mongo-based complementary foods and nutrition education which creates the demand for the nutritious products. It is envisioned to be sustained and institutionalized in the LGUs.

Congratulations to the winners of 2021 AROHRA! We celebrate your programs, which have significantly contributed to addressing prevalent health issues in the country.